منابع مشابه
How Fission Yeast Fission in the Middle
In fission yeast, we propose that the division plane may be positioned by the position of the premitotic nucleus, perhaps by a signal emanating from the nucleus. Gene products involved in the assembly of the ring and its temporal and spatial controls are beginning to be characterized. Some of these, such as mid1p, may be involved in signals that position the division site. In animal cells, the ...
متن کاملFission yeast septation
In animal cells cytokinesis relies on the contraction of an actomyosin ring that pulls the plasma membrane to create a cleavage furrow, whose ingression finally divides the mother cell into two daughter cells. Fungal cells are surrounded by a tough and flexible structure called cell wall, which is considered to be the functional equivalent of the extracellular matrix in animal cells. Therefore,...
متن کاملThe fission yeast microtubule cytoskeleton.
The Schizosaccharomyces pombe genome sequencing project (http://www. sanger.ac.uk/Projects/S_pombe/) is nearly complete, and this is likely to generate interest in fission yeast as a model system beyond its traditional strongholds in the study of the cell cycle and sexual differentiation. In many fields S. pombe will offer a useful complement to the more widely studied Saccharomyces cerevisiae,...
متن کاملDNA checkpoints in fission yeast.
The DNA integrity checkpoints ensure completion of DNA replication and DNA repair before entry into mitosis (O’Connell et al., 2000). Unreplicated DNA or unrepaired DNA will cause catastrophic chromosome segregation. The accompanying schematic shows the checkpoint proteins that monitor the state of DNA replication and DNA repair. Checkpoint proteins most probably interact with the replication c...
متن کاملCentromeric chromatin in fission yeast.
A fundamental requirement for life is the ability of cells to divide properly and to pass on to their daughters a full complement of genetic material. The centromere of the chromosome is essential for this process, as it provides the DNA sequences on which the kinetochore (the proteinaceous structure that links centromeric DNA to the spindle microtubules) assembles to allow segregation of the c...
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ژورنال
عنوان ژورنال: Cell
سال: 1996
ISSN: 0092-8674
DOI: 10.1016/s0092-8674(00)80973-3